Leucidal® Liquid Complete is a mixture of antimicrobial peptide technology. One type of the antimicrobial peptides is originally derived from the lactic acid bacteria, Leuconostoc kimchii. L. kimchii is one of 15 species of microorganisms that make up the mixed culture used for producing the Korean dietary staple known as kimchi, a type of fermented cabbage. L. kimchii is capable of restricting the growth of other microorganisms by acidifying its environment, but as is common in nature, it is not content to limit itself to a single mechanism of defense. In addition to acidifying its environment, it also produces a novel antimicrobial peptide. Using modern fermentation and bioprocessing technology, Active Micro Technologies has commercialized this antimicrobial peptide to produce Leucidal® Liquid Complete.
The other type of antimicrobial peptide is created from fermenting Cocos nucifera (Coconut) with Lactobacillus. Coconut oil has been traditionally used to treat skin disorders, yeast infections, ringworm, and even athlete’s foot. About 50% of the total fatty acid content of coconut oil are medium chain triglycerides (MCT’s) that exhibit natural antifungal activity. MCT’s, such as lauric acid, work by disrupting the cellular structures of fungus and destroying them before they can wreak havoc. During the fermentation process, lipopeptides are catabolized by the MCT’s present in coconut flesh. Active Micro Technologies has harnessed natural phytocompounds and lipopeptides from coconut to produce a novel antifungal material.
Natural antimicrobial products are similar to synthetic preservative systems in that they are effective against bacteria, however most natural antimicrobial products lack broad-spectrum effectiveness against bacteria and fungi, specifically yeast and mold. Leucidal® Liquid Complete uses a combination of peptide technology to deliver moisturizing and conditioning benefits as well as providing broad-spectrum activity to protect against bacteria, yeast, and mold in one product.
A skin moisturization study was performed using an untreated control, generic cream base, and an experimental with the same cream base containing 2.0% Leucidal® Liquid Complete.
As demonstrated by the results of this study, the addition of 2.0% Leucidal® Liquid Complete improved moisture levels by 42.01% after 24 hours and by 62.33% after four weeks when compared to the untreated control. When compared to the base cream Leucidal® Liquid Complete improved moisturization by 14.38% and after 24 hours and by 24.13% after four weeks. Based on these results, adding this innovative product provides the formulator the opportunity to capitalize on both the natural antimicrobial properties of Leucidal® Liquid Complete, as well as its ability to provide potent moisturizing benefits to the cosmetic formulation. These properties make it ideal for applications addressing numerous skin and scalp conditions.
As with all biological materials, attention must be paid to the conditions under which Leucidal® Liquid Complete is used. Based on bench-scale evaluations, as well as actual product applications, Leucidal® Liquid Complete has been found to be effective over a wide range of typical cosmetic and personal care product manufacturing conditions. Leucidal® Liquid Complete has been found to be heat stable up to70°C and active under both acidic (pH 3) and basic (pH 8) conditions.
Store at or near room temperature; Prior to use, container must be warmed to 35 – 40°C and mixed until clear. May sediment upon standing – Product may change appearance if exposed to cold temperatures during shipment or storage. If this happens, please gently warm to 45-50°C and mix until normal appearance is restored.
|INCI Nomenclature:||Leuconostoc/Radish Root Ferment Filtrate
& Lactobacillus & Cocos Nucifera (Coconut)
|Suggested Use Levels:||2-4%|
The above information is for general research purposes only and is not a representation or warranty of any kind. This material is not intended to diagnose, treat, cure or prevent any disease. The user of this material is solely responsible for determining fitness for any particular use; requesting and reviewing the applicable Material Safety Data Sheet; and compliance with all applicable laws and regulations. Terms and conditions apply.